Table 1 Literature review of cyclohexanone metabolite associated diseases
From: Robust volcano plot: identification of differential metabolites in the presence of outliers
Authors | Disease | Title of the paper | Journal name |
|---|---|---|---|
Westhoff et al., 2010 [35] | Lung cancer | Differentiation of chronic obstructive pulmonary disease (COPD) including lung cancer from healthy control group by breath analysis using ion mobility spectrometry | International Journal for Ion Mobility Spectrometry |
Wei et al., 2012 [36] | Prostate cancer | Effects of cyclohexanone analogues of curcumin on growth, apoptosis and NF-κB activity in PC-3 human prostate cancer cells | Oncology letters |
Leung et al. 2012 [37] | Breast cancer | Identification of cyclohexanone derivatives that act as catalytic inhibitors of topoisomerase I: effects on tamoxifen-resistant MCF-7 cancer cells | Investigational new drugs |
Wang et al., 2014 [26] | Breast cancer | Volatile Organic Metabolites Identify Patients with Breast Cancer, Cyclomastopathy, and Mammary Gland Fibroma | Scientific Report (Nature) |
Mochalski et al., 2014 [38] | Renal disease | Blood and breath profiles of volatile organic compounds in patients with end-stage renal disease | BMC Nephrology |
Liu et al., 2014 [39] | Lung cancer | Investigation of volatile organic metabolites in lung cancer pleural effusions by solid-phase microextraction and gas chromatography/mass spectrometry | Journal of Chromatography |
Silva et al., 2017 [40] | Breast cancer | Volatile metabolomic signature of human breast cancer cell lines | Scientific Report (Nature) |