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Fig. 1 | BMC Bioinformatics

Fig. 1

From: BS-Seeker3: ultrafast pipeline for bisulfite sequencing

Fig. 1

Summary of BS-Seeker3 pipeline and performance. a Schematic flow chart of BS Seeker 3 with improved indexing, data processing, fast alignment and post-alignment analyses (b) Metaplot of Methylation level: This metaplot presents the average methylation level distribution within a user-specified genomic structure (e.g., coding genes) in Arabiodopsis thalania. CG denotes a CpG dinucleotide, CHG denotes a cytosine next to a H where H stands for A, C, or T.and then a guanine, CHH denotes a cytosine next to two H bases (c) Average user runtime of the four aligners on 10 M simulated HiSeq 2500 Arabidopsis reads. d Percentage of the 10 M simulated HiSeq2500 reads that were mapped correctly across various reads complexity level. e Average runtime of four aligners on directional BS-seq reads from real human data [3]

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