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Fig. 4 | BMC Bioinformatics

Fig. 4

From: TIA: algorithms for development of identity-linked SNP islands for analysis by massively parallel DNA sequencing

Fig. 4

Zygosity comparison between a single-contributor and a multiple-contributor sample. Depth of coverage for SNP calls was used to determine the proportion (p) of the zygosity of the given SNPs within the profiles. Visualization of the zygosity proportions across the entire SNP profile as they map to defined zygosity regions allows the differentiation of single- and multiple-contributor samples. The plotted proportions of the single-contributor sample (a) constrain to the defined regions of homozygous reference (0.9–1.0 p, green), heterozygous (0.4–0.6 p, yellow), or homozygous variant (0–0.1 p, red) for the evaluated SNP locations. The plotted proportions of the multiple-contributor sample (b) are distributed widely between the homozygous extremes and are not constrained to the defined zygosity regions

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