Fig. 4From: A site specific model and analysis of the neutral somatic mutation rate in whole-genome cancer dataModel selection results. a Improvement of the fit during forward model selection. In each iteration, we estimate the deviance loss by cross validation to determine which explanatory variable to include in the next model. b Explanatory variables and predicted vs observed number of mutations along the genome in an example region on chromosome 3 for models 6–8. Zoom: DNA sequence, phyloP score and predicted mutation probabilities from models 5 and 6Back to article page