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Table 2 List of clonotype definitions supported by IRProfiler

From: IRProfiler – a software toolbox for high throughput immune receptor profiling

Index

Clonotype Name

Components

Comment

1

V + D + J + CDR3

(V-gene, D-gene, J-gene, CDR3-AA)

IMGT Clonotype (AA) with the allele information omitted

2

V + J + CDR3

(V-gene, J-gene, CDR3-AA)

No D-gene information; caters for D-gene assignment ambiguity

3

V + CDR3

(V-gene, CDR3-AA)

Specialized definition, focusing on V-gene

4

J + CDR3

(J-gene, CDR3-AA)

Specialized definition, focusing on J-gene

5

CDR3

(CDR3-AA)

The least detailed definition including only CDR3-AA

  1. CDR3-AA denotes the animoacid translation of the CDR3 including the anchor animoacids (104 and 118)