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Table 3 Individuals with discordant HER2 (IHC) status and HER2 (FISH) classification (individuals not expressing ER and PR are highlighted in bold)

From: Ensemble outlier detection and gene selection in triple-negative breast cancer data

Individual

ER

PR

HER2

HER2 level

HER2 status

HER2

HER2 status

Type

    

(IHC)

(IHC)

(FISH)

(IHC + FISH)

 

TCGA-LL-A5YP

0.16(+)

0.05(-)

15.10

1+

-

+

+

non-TNBC

TCGA-A2-A0EQ

2.13(-)

0.04(-)

30.5

3+

+

-

-

TNBC

TCGA-BH-A18T

0.61(-)

0.04(-)

29.35

2+

+

-

-

TNBC

TCGA-AO-A0JL

0.63(-)

0.08(-)

63.60

1+

-

+

+

non-TNBC

TCGA-AN-A0XV

110.33(+)

3.50(+)

22.17

2+

+

-

-

non-TNBC

TCGA-AO-A12C

18.88(+)

3.60(+)

95.67

3+

+

-

-

non-TNBC

TCGA-BH-A18Q

2.83(-)

1.10(-)

20.93

 

+

-

-

TNBC

TCGA-LL-A5YL

9.84(+)

0.52(-)

55.32

3+

+

-

-

non-TNBC

TCGA-E2-A10A

59.40(+)

9.89(+)

32.99

2+

+

-

-

non-TNBC

TCGA-AO-A03L

14.71(+)

1.35(+)

58.72

2+

+

-

-

non-TNBC

TCGA-AO-A12G

40.39(+)

1.80(+)

45.03

2+

+

-

-

non-TNBC

TCGA-BH-A1EX

5.50(+)

0.28(+)

41.46

 

+

-

-

non-TNBC

TCGA-BH-A0AU

37.14(+)

16.19(+)

51.79

 

+

-

-

non-TNBC

TCGA-A2-A04U

0.02(-)

0.02(-)

9.64

1+

-

+

+

non-TNBC

TCGA-AN-A0XW

13.96(+)

5.32(+)

22.04

2+

+

-

-

non-TNBC

  1. Individuals marked with asterisks show no concordance regarding HER2 labeling by different testing and are misclassified by logistic regression based on the 3 variables clinically used to classify breast cancer patients into TNBC