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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Integrative analysis and machine learning on cancer genomics data using the Cancer Systems Biology Database (CancerSysDB)

Fig. 3

In-depth analysis of the dynamics of the TCA pathway in KIRP cancer patients. Interactive view bee-swarm scatter plot on the Tricarboxylic acid cycle (TCA) pathway from KIRP cancer patients is shown. The log2-fold changes are averaged for patients according to tumor grade (Stage I-IV). The dashboard gives the number of patients per grade and allows for further filtering according to gender or vital status (see also Additional file 2: Figure S1). a The SUCLG1 gene is selected (pink bubble in bee-swarm scatter plot). b The SUCLG2 gene is selected. Both genes show a strong, averaged down-regulation in Stage IV KIRP cancer patients (see Table 4 for averaged log2-fold changes)

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BMC Bioinformatics

ISSN: 1471-2105

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