From: Robust joint score tests in the application of DNA methylation data analysis
Scenarios | Outlier | α(%) | jointLRT | KS | AW | iAW.Lev | iAW.BF | iAW.TM |
---|---|---|---|---|---|---|---|---|
eqM&eqV | No | 5 | 5.1 | 3.4 | 5.1 | 5.1 | 5.0 | 5.1 |
(Type I error) | No | 1 | 1.0 | 0.5 | 1.1 | 1.0 | 1.0 | 1.1 |
No | 0.5 | 0.5 | 0.4 | 0.6 | 0.6 | 0.5 | 0.6 | |
diffM&eqV | No | 5 | 97.3 | 95.5 | 97.1 | 97.1 | 97.2 | 97.2 |
No | 1 | 90.2 | 84.9 | 89.4 | 89.8 | 90.0 | 89.7 | |
No | 0.5 | 85.3 | 75.0 | 84.3 | 83.1 | 83.8 | 83.6 | |
eqM&diffV | No | 5 | 90.0 | 25.1 | 87.3 | 84.1 | 83.8 | 83.8 |
No | 1 | 74.3 | 6.1 | 65.7 | 63.5 | 62.9 | 62.6 | |
No | 0.5 | 66.3 | 2.4 | 55.2 | 51.6 | 52.0 | 52.5 | |
diffM&diffV | No | 5 | 83.2 | 63.9 | 81.0 | 79.3 | 79.2 | 79.3 |
No | 1 | 63.7 | 36.8 | 59.9 | 56.9 | 56.8 | 56.3 | |
No | 0.5 | 53.9 | 24.5 | 48.8 | 45.5 | 46.3 | 46.2 | |
eqM&eqV | Yes | 5 | 12.2 | 3.2 | 3.7 | 4.8 | 4.8 | 4.8 |
(Type I error) | Yes | 1 | 3.7 | 0.5 | 0.5 | 0.9 | 0.9 | 1.0 |
Yes | 0.5 | 2.3 | 0.4 | 0.3 | 0.4 | 0.4 | 0.4 | |
diffM&eqV | Yes | 5 | 95.6 | 94.9 | 98.4 | 98.1 | 98.1 | 98.1 |
Yes | 1 | 83.0 | 86.6 | 94.5 | 92.3 | 92.7 | 92.4 | |
Yes | 0.5 | 77.5 | 76.9 | 91.0 | 89.4 | 90.0 | 89.3 | |
eqM&diffV | Yes | 5 | 46.3 | 16.7 | 54.3 | 69.3 | 68.8 | 68.9 |
Yes | 1 | 20.3 | 5.3 | 31.5 | 43.0 | 43.5 | 43.2 | |
Yes | 0.5 | 15.1 | 2.2 | 22.8 | 36.0 | 36.8 | 36.1 | |
diffM&diffV | Yes | 5 | 54.6 | 58.4 | 75.5 | 78.4 | 78.5 | 78.7 |
Yes | 1 | 26.5 | 38.2 | 56.9 | 56.1 | 57.2 | 57.0 | |
Yes | 0.5 | 20.3 | 25.8 | 47.5 | 48.4 | 50.4 | 49.1 |