Fig. 4

Neuronal heterogeneity a Heat map representation of heterogeneous pathways identified by HeteroPath from hippocampal, cingulate cortex, and amygdala neurons. The orange to yellow to white gradient represents increasing expression of the pathway with orange representing minimal expression while the white represents high expression of the pathway. Upregulated tissue-specific pathways are highlighted in colored boxes. b, c The results of enriched PGSEA and GSEA pathways from hippocampal, cingulate cortex, and amygdala neurons. The orange to yellow to white gradient represents increasing expression of the pathway with orange representing minimal expression while the white represents high expression of the pathway. d A Venn diagram displaying the number of overlapping and unique KEGG pathways identified by HeteroPath, PGSEA, and GSEA