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Table 2 Eighteen gene-gene interactions and, interaction type, and another participating pathway of each relationship

From: Relation extraction for biological pathway construction using node2vec

Relation no.

Starting entity

Target entity

Interaction type

Another participating pathway

1

ADIPO

GLUT4

Indirect

Adipocytokine signaling pathway

2

INS

INSR

Direct

–

3

INSR

IRS1/IRS

Direct

–

4

IRS1/ IRS

PI3K

Direct

–

5

INSR

SOCS

Direct

–

6

SOCS

IRS1/IRS

Direct

–

7

INSR

ERK

Indirect

Insulin signaling pathway

8

ERK

IRS1/IRS

Indirect

Insulin signaling pathway

9

PI3K

GLUT4

Indirect

Insulin signaling pathway

10

PI3K

mTOR

Indirect

Insulin signaling pathway

11

PI3K

PKC

Indirect

Insulin signaling pathway

12

TNFA

IKK

Indirect

Adipocytokine signaling pathway

13

TNFA

JNK

Indirect

Adipocytokine signaling pathway

14

TNFA

mTOR

Indirect

Adipocytokine signaling pathway

15

IKK

IRS1/IRS

Direct

–

16

JNK

IRS1/IRS

Direct

–

17

PKCZ

IRS1/IRS

Direct

–

18

PKCD/E

IRS1/IRS

Direct

–