Table 3 Extended paths and directed links in each expanded path
From: Relation extraction for biological pathway construction using node2vec
Relation no. | Extended path based on the KEGG pathways | Direct relationship no. | Direct paths in the expanded path |
|---|---|---|---|
1 | ADIPO-ADIPOR1-AMPK-GLUT4 | 1 | ADIPO-ADIPOR |
2 | AMPKK- AMPK | ||
7 8 | INSR-SHC-GRB2-SOS-Ras-Raf-MEK1/2-ERK1/2 IRS-GRB2-SOS-Ras-Raf-MEK1/2-ERK1/2 | 3 | INSR-SHC |
4 | SHC-GRB2 | ||
5 | GRB2-SOS | ||
6 | SOS-Ras | ||
7 | Ras-Raf | ||
8 | Raf-MEK1/2 | ||
9 | MEK1/2-ERK1/2 | ||
10 | IRS-GRB2 | ||
9 10 11 | PI3K-PDK1/2-AKT-GLUT4 PI3K-PDK1/2-PKC-GLUT4 PI3K-PDK1/2-AKT-mTOR PI3K-PDK1/2-PKC | 11 | PI3K-PDK1/2 |
12 | PDK1/2-AKT | ||
13 | AKT-GLUT4 | ||
14 | PDK1/2-PKC | ||
15 | PKC-GLUT4 | ||
16 | AKT-mTOR | ||
12 13 14 | TNFA-TNFR1-TRADD-TRAF2-IKK TNFA- TNFR1-TRADD-TRAF2 -JNK TNFA-TNFR1-TRADD-TRAF2-mTOR | 17 | TNFA-TNFR1 |
18 | TNFA-TNFR2 | ||
19 | TNFR1-TRADD | ||
20 | TRADD-TNFR2 | ||
21 | TNFR2-TRAF2 |