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Fig. 2 | BMC Bioinformatics

Fig. 2

From: polyClustR: defining communities of reconciled cancer subtypes with biological and prognostic significance

Fig. 2

Breast cancer subtypes and their association with intrinsic subtypes – application of polyClustR. a-c Heatmaps of similarity of each set of clusters generated by consensus a NMF, b HC and c KM to the known breast cancer subtypes of each sample using 118 breast cancer samples from the published Chin dataset [21] is shown. A hypergeometric test was used to test the significance of overlap between the clusters and the known subtypes. bNMF, bHC and bKM represent NMF, HC and KM breast cancer subtypes, respectively. Norm – normal-like, LumA – luminal A and LumB – luminal B subtypes. FDR – false discovery rate

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BMC Bioinformatics

ISSN: 1471-2105

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