Fig. 4

Subtype communities of uveal melanoma identified using polyClustR. a A hypergeometric (HYP) test and b PMI was used to assess the overlap between each pair of clusters using the uveal melanoma dataset [22]. The resulting FDR corrected p values were plotted as edge colours/weights in this network, with each node representing a cluster. The size of each node represents the number of samples that cluster contains, and those nodes in a lighter shade represent clusters with associations to known subtypes that are not significant (FDR corrected p > 0.05). Gray shading marks dense groups of clusters as defined by network community detection. mHYP and mPMI represent HYP and PMI subtype melanoma communities, respectively. Average silhouette width is shown for each of the subtype communities