TY - JOUR AU - Fang, Li AU - Hu, Jiang AU - Wang, Depeng AU - Wang, Kai PY - 2018 DA - 2018/05/23 TI - NextSV: a meta-caller for structural variants from low-coverage long-read sequencing data JO - BMC Bioinformatics SP - 180 VL - 19 IS - 1 AB - Structural variants (SVs) in human genomes are implicated in a variety of human diseases. Long-read sequencing delivers much longer read lengths than short-read sequencing and may greatly improve SV detection. However, due to the relatively high cost of long-read sequencing, it is unclear what coverage is needed and how to optimally use the aligners and SV callers. SN - 1471-2105 UR - https://doi.org/10.1186/s12859-018-2207-1 DO - 10.1186/s12859-018-2207-1 ID - Fang2018 ER -