Core Hunter 3: flexible core subset selection

BMC Bioinformatics

Table 2 Comparison of Core Hunter 2 and 3

CH2 maximizes a weighted index including average and minimum pairwise distance, with equal weight, while CH3 maximizes E-NE. Mean E-NE, DMIN, runtime and corresponding standard deviations are reported for 10 independent executions. The highest obtained E-NE and DMIN value per dataset is shown in bold. CH3 was terminated when no improvements were found during 10 s. For CH2, two alternatives were considered: (a) the same stop condition as for CH3 (CH2); and (b) an absolute runtime limit that was empirically determined per dataset to ensure that the LR replica of MixRep terminated in each run (CH2L)

ISSN: 1471-2105