MICOP: Maximal information coefficient-based oscillation prediction to detect biological rhythms in proteomics data

Table 1 Novel oscillating protein candidates of C57BL/6 J [9] detected by MICOP

Gene name	Species	Condition	Tissue	Reference
Acot8	–	–	–	–
Acox1	Homo sapiens	LL	blood	[36]
	Mus musculus	LD	liver/SCN	[37, 38]
Acsl5	Mus musculus	DD/LD	liver/SCN	[39]
	Mus musculus	LD	SCN	[37]
Akr1c14	Mus musculus	LD	liver	[40]
	Mus musculus	DD	cartilage tissue	[41]
Cbs	Mus musculus	DD/LD	liver	[42,43,44,45]
	Mus musculus	LD	SCN	[37]
	Homo sapiens	LL	blood	[36]
Cct8	Mus musculus	LD	SCN	[37]
Ces1b	–	–	–	–
Chid1	Mus musculus	DD/LD	liver/SCN	[46]
Cxadr	Mus musculus	DD/LD	liver/SCN	[42]
Cyp4f14	–	–	–	–
Gns	Homo sapiens	LL	blood	[36]
	Mus musculus	DD/LD	liver	[40]
Golgb1	Mus musculus	DD/LD	liver/SCN	[37, 40, 47]
Gpx3	–	–	–	–
Hars	Mus musculus	LD	liver	[40]
Hrg	–	–	–	–
Mfap4	–	–	–	–
Mug1	Mus musculus	DD	liver	[42]
Pdcd6	Mus musculus	LD	liver/SCN	[37, 40, 47],
Ptms	Mus musculus	LD	SCN	[37]
Safb	–	–	–	–
Serpina6	Mus musculus	DD/LD	liver	[44]
Sf3b2	Mus musculus	LD	telogen epidermis	[46]
Slc9a3r1	Mus musculus	DD/LD	liver	[46]
Snrpd3	Mus musculus	LD	liver	[47]
Stk38	Mus musculus	DD	liver	[46]
	Mus musculus	LD	SCN	[37]
Tpr	Mus musculus	DD/LD	liver	[40, 46]
Txndc15	Mus musculus	DD/LD	liver	[46, 47]
	Mus musculus	LD	SCN	[37]
Ubl4a	Mus musculus	LD	SCN	[37]
	Mus musculus	DD	liver	[46]
Uox	Mus musculus	DD/LD	liver	[39, 40, 42, 47]
Ythdf2	Mus musculus	LD	liver	[47]

Novel oscillating protein candidates identified by MICOP from time-series proteomics data of C57BL/6 J [9] and a list of previous papers that have experimentally demonstrated that gene expression oscillates in transcriptome analysis. LD stands for the daily 24-h light-dark (LD) cycle and DD stands for constant darkness conditions. Hyphens indicate that we could not find previous consistent works which prove the mRNA oscillation

ISSN: 1471-2105