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Fig. 4 | BMC Bioinformatics

Fig. 4

From: Benchmarking differential expression analysis tools for RNA-Seq: normalization-based vs. log-ratio transformation-based methods

Fig. 4

Differential expression analysis of Williams et al. data. This figure shows the precision (y-axis) versus the recall (x-axis) of a complete differential expression analysis applied to real RNA-Seq data. The “truth set” is established using a microarray reference (see Methods). The acronyms clr, iqlr, and ii1 describe log-ratio transformations (see Methods). The acronyms slFMD, slQUASI, stsl, and stst describe alignment and quantification procedures (see Methods). Translucent data points show performance calculated from a previously published systematic benchmark. ALDEx2 tends toward higher precision and lower recall

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