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Fig. 6 | BMC Bioinformatics

Fig. 6

From: Benchmarking differential expression analysis tools for RNA-Seq: normalization-based vs. log-ratio transformation-based methods

Fig. 6

Between-group differences of Rollins et al. data. This figure shows the mean (or median) absolute between-group differences for differentially expressed transcripts (y-axis) versus the differential expression method (x-axis) (organized by the alignment and quantification procedure used). Between-group differences are reported as measured by the respected method (i.e., mean for edgeR and median for ALDEx2). The acronyms clr, iqlr, and ii1 describe log-ratio transformations (see Methods). The acronyms slFMD, slQUASI, and stsl describe alignment and quantification procedures (see Methods). Differentially expressed transcripts selected based on an FDR < 0.05 as calculated by the respective method. Figure prepared from Rollins et al. data

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