HiCcompare: an R-package for joint normalization and comparison of HI-C datasets

BMC Bioinformatics

Table 2 Gene enrichment results for HiCcompare analyses

Pathway	1 MB	100 KB	50 KB
Systemic lupus erythematosus	3.807e-06	6.302e-17	1.025e-02
Antigen processing and presentation	3.807e-06	6.808e-01	9.974e-01
Staphylococcus aureus infection	8.170e-03	2.354e-01	7.604e-01
Viral myocarditis	8.170e-03	1.038e-01	9.657e-01
Allograft rejection	8.170e-03	1.518e-01	9.974e-01
Viral carcinogenesis	3.327e-02	3.659e-08	3.273e-01
Pathways in cancer	9.162e-01	2.236e-02	9.409e-01

KEGG pathways and their corresponding FDR-corrected p-values for the enrichment analyses of HiCcompare-detected differences at 1 MB, 100 KB, and 50 KB resolutions. Differentially interacting regions detected by HiCcompare were intersected with gene locations, and the overlapping genes were tested for enrichment using EnrichR [37]

ISSN: 1471-2105