Fig. 3
From: PRS-on-Spark (PRSoS): a novel, efficient and flexible approach for generating polygenic risk scores
PRSice v1.25 and PRSoS performance across datasets. Bar plot shows the results of the performance test comparing running PRSice v1.25 and PRSoS across the datasets. Error bars indicate standard deviations. Numbers in boxed inserts indicate the size of the genotype data input. †Note that the file sizes used for the Imputed PP are same for PRSice v1.25 and PRSoS, thus illustrating the processing speed difference with same file size input. Imputed PP = imputed posterior probabilities, Imputed HC = imputed posterior probabilities converted to “hard calls”, Array Data = observed genotypes. Significance values derived from paired t-tests