Fig. 1
From: An infrastructure for precision medicine through analysis of big data
Macro architecture. The infrastructure consists of four layers: 1) Collection Layer, responsible for the data collection; 2) Anonymization Layer, responsible for the anonymization of the data to preserve the confidentiality of patient sensitive data; 3) Machine Learning and Aggregation Layer, responsible to merge data from different sources and manage the literal text; 4) Big Data Analysis Layer, responsible for the analysis of the data