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Fig. 8 | BMC Bioinformatics

Fig. 8

From: A novel computational method for automatic segmentation, quantification and comparative analysis of immunohistochemically labeled tissue sections

Fig. 8

Tissue-based registration of tissue samples and computation of concentration regions. a-c metastatic melanoma tissue marked with CD3 (a), CD8 (b), and CD14 (c) antibodies stained in reddish color. e overlapped markers after registration; f overlapped concentration regions after registration. f-h concentration regions of markers CD3 (f), CD8 (g), and CD14 (h). In this case, the GTRO before registration equals 81.2%, while it increases to 97.4% after registration

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