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Table 1 Numbers of significant and not-significant siRNAs from the primary whole genome siRNA screen (columns) and a secondary validation screen (rows) on two cell lines using an empirical Bayes model (FDR ≤ 0.05) on either robust z-scores or rscreenorm data

From: Rscreenorm: normalization of CRISPR and siRNA screen data for more reproducible hit selection

  

Primary screen

 

Robust z-scores

 

Not significant

Significant

Total

Secondary screen

Not significant

5

168

173

 

Significant

33

99

132

Total

 

38

267

305

Rscreenorm

    

Secondary screen

Not significant

78

103

181

 

Significant

33

91

124

Total

 

111

194

305

  1. The screens involved 21121 and 305 siRNAs each, respectively