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Fig. 8 | BMC Bioinformatics

Fig. 8

From: HebbPlot: an intelligent tool for learning and visualizing chromatin mark signatures

Fig. 8

Signatures of active enhancers. Enhancers were collected from a study by Rajagopal et al. [54] and from the Fantom Project. A HebbPlot was generated from the enhancers of each tissue. The HebbPlots of H1 and IMR90, for which more than 20 marks are known, show that several marks are present around active enhancers. Usually, H3K4me1 has a stronger signal around enhancers than H3K4me3; however there are some exceptions, e.g. foetal brain. H3K9ac and H3K27ac are present around enhancers, but H3K9me3, H3K27me3, and H3K36me3 are very weak or absent from enhancers. These plots show that chromatin signatures of enhancers active in different tissues are similar, but not identical. a H1, b IMR90, c Liver, d Foetal brain, e Foetal small intestine, f Left ventricle, g Lung, h pancreas

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