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Table 3 Overall Performance of The Denoising Methods Using the Real WES Data

From: Noise cancellation using total variation for copy number variation detection

Denoising Methods

Amplified CNVs

Deleted CNVs

Sensitivity

FDR

Specificity

Sensitivity

FDR

Specificity

Before applying denoising method

50.99%

42.06%

80.45%

60.37%

64.32%

56.71%

After applying DWT

68.81%

41.65%

79.92%

77.65%

54.32%

72.23%

After applying Taut String

69.52%

40.21%

84.51%

79.93%

50.72%

77.25%