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Fig. 1 | BMC Bioinformatics

Fig. 1

From: Predicting variant deleteriousness in non-human species: applying the CADD approach in mouse

Fig. 1

a-d) ROC-AUC scores of the four different mCADD models evaluated on seven different subsets of the mouse held-out test set reflecting different genomic regions and/or functional annotations. e, f) Seven different subsets of the mouse held-out test set evaluated by glire- and vertebrate based PhastCons scores, respectively. g) Missense mutations of the mouse held-out test set evaluated by SIFT. h) The sub sets of the mouse held-out test set evaluated by hCADD*.: I) all data, II), not-transcribed, III) transcribed, IV) transcribed but not translated, V) translated, VI) translated and synonymous, and VII) translated and missense. The different models are indicated at the top of the panel. All displayed scores are ROC-AUC

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