Fig. 3

Sequence alignments of lambda spanin families. a and c show alignments of i-spanin and o-spanin sequences (periplasmic domains only) of the lambda family respectively. The alignments of i-spanin sequences from 1720a-02 and H-19B with respect to the lambda i-spanin are shown separately in (b) as their i-spanin sequences were significantly longer compared to other members. Secondary structure predictions for respective spanins from lambda are shown above each alignment. The secondary structure predictions for i-spanins from H19B and 1720a-02 are shown above and below respectively, in the additional alignment in (b). Grey rectangles indicate alpha helices and black arrows indicate beta sheets. Conservation at different positions is shown below with colors (Red indicates maximum conservation and blue indicates least conservation). A scale indicating the relative position of the residues and the approximate size of various domains is shown above the alignments