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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Molecular dynamics and structure function analysis show that substrate binding and specificity are major forces in the functional diversification of Eqolisins

Fig. 2

Excerpt of Multiple Sequence Alignment Eqolisins. Indicated are the sequences for which a structure has been resolved (PDB IDs 2IFW, 1Y43) as well a number of sequences selected to show overall sequence variation. The lower block contains sequences that were removed upon sequence scrutiny as described in the main text. The rulers indicate positions of hallmark residues and or positions described under the sequence scrutiny. Encircled cysteines are involved in disulfide bridges, indicated by lines. Shading indicates conservation (100% black; 80% dark-gray, 60% light-gray)

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