Identifying protein complexes based on node embeddings obtained from protein-protein interaction networks

BMC Bioinformatics

Table 5 Experimental results obtained by using RF to filter the candidate complexes which are predicted from the modified HPRD network by adding edges with different simi-thres

Simi-thres	No. of added edges	No. of complexes	Precision	Recall	F-score	Δ
0.65	7889	717	0.6137	0.2893	0.3932	-0.0280
0.66	7572	824	0.6104	0.3454	0.4412	+0.0200
0.67	7174	829	0.6164	0.3487	0.4455	+0.0243
0.68	6531	940	0.6266	0.3983	0.4870	+0.0658
0.69	5546	952	0.6313	0.4003	0.4899	+0.0687
0.70	4121	1030	0.6544	0.4168	0.5092	+0.0880
0.71	2522	1021	0.6513	0.4148	0.5068	+0.0856
0.72	1390	1028	0.6566	0.4207	0.5129	+0.0917
0.73	850	1015	0.6611	0.4155	0.5102	+0.0890
0.74	583	1024	0.6563	0.4188	0.5113	+0.0901
0.75	447	1017	0.6608	0.4168	0.5111	+0.0899

Δ denotes the improvement of F-score compare with using SLPC alone. Bold values denote the best scores corresponding to the specific metric

ISSN: 1471-2105