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Fig. 2 | BMC Bioinformatics

Fig. 2

From: Computational discovery of direct associations between GO terms and protein domains

Fig. 2

Schematic illustration of edge discovery. In a typical instantiation, X is a set of MF GO terms, Y a set of Pfam domains, and Z a set of UniProtKB/SwissProt sequences. E1 are edges derived from the MF GO annotation of UniProtKB/SwissProt sequences, E2 are edges derived from the domain contents of UniProtKB/SwissProt sequences, \(E_{3}^{*}\) is the enriched set of edges, derived from initial \(E_{3}^{\null }\) that included a limited number of edges (represented here by (x1,y1)), derived from the InterPro manually curated MF GO annotations of Pfam domains. \(E_{3}^{*}\) contains all newly discovered MF GO-Pfam associations represented here by (x2,y2)

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