Fig. 2From: Computational discovery of direct associations between GO terms and protein domainsSchematic illustration of edge discovery. In a typical instantiation, X is a set of MF GO terms, Y a set of Pfam domains, and Z a set of UniProtKB/SwissProt sequences. E1 are edges derived from the MF GO annotation of UniProtKB/SwissProt sequences, E2 are edges derived from the domain contents of UniProtKB/SwissProt sequences, \(E_{3}^{*}\) is the enriched set of edges, derived from initial \(E_{3}^{\null }\) that included a limited number of edges (represented here by (x1,y1)), derived from the InterPro manually curated MF GO annotations of Pfam domains. \(E_{3}^{*}\) contains all newly discovered MF GO-Pfam associations represented here by (x2,y2)Back to article page