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Table 4 Genes with the largest fold change between hNSC and NHA cell lines (p-values)

From: Expression analysis of RNA sequencing data from human neural and glial cell lines depends on technical replication and normalization methods

aLog2Transformed RPKM Normalized aTMM Normalized UQS Normalized
PARD6G-AS1 (4.7 × 10−3) HNRNPU (2.8 × 10−10) PARD6G-AS1 (4.7 × 10− 3) ZNF496 (6.1 × 10−7)
HNRNPU (1.6 × 10−7) ZNF496 (2.2 × 10−8) HNRNPU (1.5 × 10−7) PARD6G-AS1 (1.9 × 10−2)
RNF126 (4.8 × 10−4) PARD6G-AS1 (5.0 × 10− 3) RNF126 (4.9 × 10− 4) HNRNPU (1.8 × 10− 10)
OR4F17 (2.8 × 10− 3) RNF126 (2.0 × 10− 4) OR4F17 (2.8 × 10− 3) ACTB (1.1 × 10− 3)
LINC01002 (2.3 × 10− 3) OR4F17 (2.6 × 10− 3) LINC01002 (2.3 × 10− 3) RNF126 (1.6 × 10− 3)
LOC105376854 (2.7 × 10− 4) LOC105376854 (9.6 × 10− 5) LOC105376854 (2.7 × 10− 4) OR4F17 (1.2 × 10− 2)
HCN2 (5.8 × 10− 4) MBD3 (6.1 × 10− 6) HCN2 (5.9 × 10− 4) LINC01002 (1.0 × 10− 2)
PRSS57 (5.3 × 10− 4) ARHGAP45 (1.2 × 10− 5) PRSS57 (5.5 × 10− 4) ARHGAP45 (2.1 × 10− 4)
MBD3 (3.9 × 10− 5) CIRBP-AS1 (8.0 × 10− 6) MBD3 (4.1 × 10− 5) ADAMTSL5 (6.5 × 10− 5)
ARID3A (2.4 × 10− 4) ADAMTSL5 (8.3 × 10− 6) CIRBP-AS1 (4.8 × 10− 5) ARID3A (7.2 × 10− 4)
  1. Significanta differentially expressed genes were only uncovered following log2 transformation and TMM normalization (Benjamini-Hochberg FDR = 10%). Common genes shown in italics