Skip to main content
Fig. 3 | BMC Bioinformatics

Fig. 3

From: Drug candidate identification based on gene expression of treated cells using tensor decomposition-based unsupervised feature extraction for large-scale data

Fig. 3

How to infer target proteins. By means of TD-based unsupervised FE, a set of genes with the expression level alterations following the activity of specific compounds can be inferred (‘inferred compounds’ and ‘inferred genes’ in Table 1), but a compound’s target genes (blue rectangle, ‘predicted targets’ in Table 1) cannot. Nonetheless, a list of inferred gene sets can be compared with that of the single-gene perturbations taken from Enrichr’s ‘Single Gene Perturbations category from GEO up’, enabling identification of the compound’s target genes

Back to article page