Fig. 1From: Application of fourier transform and proteochemometrics principles to protein engineeringPrinciples of statistical methods used to model structure or sequence to activity relationship (Damborský and Brezovsky [41] reproduced with permissions). a Schema illustrating the principles behind Quantitative Structure to Function Relationship method whereby numerical descriptors derived from structure are regressed on the activity data (yellow column). b Principles behind Protein Sequence to Activity Relationship methods whereby numerical descriptors derived from sequence are regressed on the activity dataBack to article page