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Fig. 3 | BMC Bioinformatics

Fig. 3

From: Discovering the ‘Dark matters’ in expression data of miRNA based on the miRNA-mRNA and miRNA-lncRNA networks

Fig. 3

Construction of the BMMN in BRCA. The BRCA is used as the example. We built ISMMNs and ISMLN for the 755 breast cancer samples, counted the number of miRNA-mRNA and miRNA-lncRNA interactions that appeared in 755 breast ISMMNs and ISMLN, and ranked them in descending order. The BRCA score of every miRNA-mRNA and miRNA-lncRNA interaction can be calculated. Finally, the BMMN and BMLN of BRCA was constructed by selecting the miRNA-mRNA and miRNA-lncRNA interactions with high BRCA scores

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BMC Bioinformatics

ISSN: 1471-2105

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