Table 2 Significant disease associated genes in the chemokine receptor family
From: Multi–omic analysis of signalling factors in inflammatory comorbidities
Disease | Up–regulated DEG | Down–regulated DEG | Up–regulated DMG | Down–regulated DMG |
|---|---|---|---|---|
Allergy | CCR6, CCR7 | — | — | CXCR4 |
Asthma | CXCR7 | — | — | — |
CFS | CXCR4, CX3CR1 | — | — | — |
Colitis | CXCR4 | XCR1, CCRL1 | CCR4 | CCR7,CMKLR1 |
Colon Cancer | — | — | — | — |
Crohn | — | — | — | — |
RA | CXCR1, CXCR2, CXCR4 | — | — | — |
SLE | CCR5, CMKLR1, CXCR2, CXCR4, CX3CR1, CCR1 | XCR1 | — | — |
T2D | CXCR4 | — | — | CXCR4 |