Table 3 Significant disease associated genes in the TNF receptor family
From: Multi–omic analysis of signalling factors in inflammatory comorbidities
Disease | Up–regulated DEG | Down–regulated DEG | Up–regulated DMG | Down–regulated DMG |
|---|---|---|---|---|
Allergy | — | — | TNFRSF4 | — |
Asthma | TNFRSF21 | — | — | — |
CFS | TNFRSF1A, CD27, TNFRSF1B | TNFRSF11B | TNFRSF4 | — |
Colitis | TNFRSF14, CD27, TNFRSF1B | — | — | — |
Colon Cancer | — | — | RELT, TNFRSF4, TNFRSF13B | TNFRSF12A |
Crohn | TNFRSF14, TNFSRF1B | — | — | — |
RA | — | — | RELT, TNFSRF4, TNFRSF17, TNFRSF13B, EDA2R, EDAR | — |
SLE | TNFRSF1B | — | TNFRSF4, EDA2R | — |
T2D | TNFRSF21, TNFRSF12A | TNFRSF17 | — | — |