|
Category
|
Name
|
Pearson’s r
|
p-value
|
|---|
|
B
|
SIFT
|
− 0.493
|
7.87E-19
|
|
B
|
LRT
|
−0.486
|
2.76E-18
|
|
B
|
MutationAssessor
|
−0.573
|
5.22E-26
|
|
B
|
FATHMM
|
−0.054
|
1.85E-01
|
|
B
|
PROVEAN
|
−0.546
|
1.86E-23
|
|
Meta
|
VEST3
|
−0.699
|
1.08E-42
|
|
Meta
|
MetaSVM
|
0.285
|
1.00E + 00
|
|
Meta
|
MetaLR
|
−0.482
|
5.77E-18
|
|
Meta
|
M-CAP
|
−0.255
|
8.09E-06
|
|
ML
|
POLYPHEN2 HDIV
|
−0.672
|
1.67E-38
|
|
ML
|
POLYPHEN2 HVAR
|
−0.648
|
4.53E-35
|
|
ML
|
MutationTaster
|
−0.499
|
2.42E-19
|
|
ML
|
CADD
|
−0.595
|
1.78E-28
|
|
ML
|
DANN
|
−0.388
|
8.51E-12
|
|
ML
|
FATHMM-MKL
|
−0.434
|
1.35E-14
|
|
ML
|
GenoCanyon
|
−0.282
|
7.95E-07
|
|
n
|
GERP++
|
−0.405
|
9.34E-13
|
|
Cons
|
phyloP7way vertebrate
|
−0.441
|
4.79E-15
|
|
Cons
|
phyloP20way mammalian
|
−0.214
|
1.54E-04
|
|
Cons
|
phastCons7way vertebrate
|
−0.486
|
2.55E-18
|
|
Cons
|
phastCons 20 way mammalian
|
−0.256
|
7.35E-06
|
|
Cons
|
SiPhy 29way logOdds
|
−0.389
|
7.65E-12
|
- Pearson’s r correlation coefficient between rank scores and residual activities, together with the associated p-value for significance scoring, for all the predictors used by wANNOVAR. Bold text is used for the highest correlations. Categories are B for “biologically based prediction method”, ML for “Machine Learning based prediction method”, Meta for “Meta prediction method” and Cons for “Conservation scoring tool”
