Skip to main content

Table 1 A summary of the complexity levels of the four synthetic data sets

From: Comparing the performance of selected variant callers using synthetic data and genome segmentation

 

Set 1

Set 2

Set 3

Set 4

Mutation types

SNV, structural variation (SV) (deletions, duplications, inversions)

SNV, SV (deletions, duplications, insertions, inversions)

SNV, SV (deletions, duplications, insertions, inversions) & INDEL

SNV, SV (deletions, duplications, inversions) & INDEL

Number of Somatic SNVs

3535

4322

7903

16,268

Cellularity

100%

80%

100%

80%

Subclone variant allele frequencies (VAFs)

N/A

N/A

50%, 33%, 20%

50%, 35% (effectively 30% and 15% due to cellularity)