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Fig. 7 | BMC Bioinformatics

Fig. 7

From: Deblender: a semi−/unsupervised multi-operational computational method for complete deconvolution of expression data from heterogeneous samples

Fig. 7

TCGA breast cancer RNA-Seq dataset with 1093 primary tumor mixed samples including 3 defined tissue components (normal, stromal, tumor). Evaluation of the unsupervised mode of Deblender* (customized setting – S1) and MMAD* methods (customized setting – default percentile) relative to histological estimates. Correlation is also reported for subsets of samples with known molecular subtype. Pearson correlation (r) results per tissue component, Deblender*: Normal: − 0.051, Stromal: − 0.022, Tumor: -0.061, MMAD: Normal: − 0.041, Stromal: 0.071, Tumor: − 0.026

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BMC Bioinformatics

ISSN: 1471-2105

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