Fig. 3
From: Learning protein binding affinity using privileged information
Feature analysis using SHAP. The impact of 2-mer features on model output is shown using SHAP values. The plot shows the top 20 2-mers for the Ligand (L) or Receptor (R) by the sum of their SHAP values over all samples. Feature value is shown in color (Red: High; Blue: Low) reveals for example that a high value of L (EK) (Counts of ‘EK’ in a protein sequence designated as ligand) contributes more for predicting low binding affinity complexes