Table 6 The performance of best docking poses having different number of rotatable bonds in term of FNAT; poses generated by different methods on the PPDbench dataset
From: Benchmarking of different molecular docking methods for protein-peptide docking
Docking methods | Rotatable bonds | ||
|---|---|---|---|
0–40 | 41–60 | > 60 | |
ATTRACT-20a | 62.90 | 63.85 | 79.91 |
ATTRACT-1 | 40.93 | 38.55 | 48.25 |
Hex-20 | 31.96 | 29.78 | 33.08 |
Hex-1 | 08.12 | 15.06 | 13.58 |
ZDOCK-20 | 78.51 | 65.30 | 71.41 |
ZDOCK-1 | 41.15 | 42.98 | 44.83 |
PatchDock-20 | 55.09 | 59.25 | 46.95 |
PatchDock-1 | 27.00 | 22.02 | 14.37 |
pepATTRACT-20 | 43.60 | 21.69 | 22.41 |
pepATTRACT-1 | 22.03 | 09.26 | 08.70 |
FRODOCK-20 | 73.42 | 69.47 | 75.08 |
FRODOCK-1 | 49.78 | 46.17 | 53.75 |