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Fig. 7 | BMC Bioinformatics

Fig. 7

From: RefCell: multi-dimensional analysis of image-based high-throughput screens based on ‘typical cells’

Fig. 7

Integrating information from all channels: Percentage of healthy-like cells in one channel vs. percentage of cells classified as healthy-like in the other three channels. Each circle stands for a sample (green: GFP-progerin repressed, red: GFP-progerin expressing, blue: siRNA). The size of the circle is proportional to the percentage of cells that are classified as healthy-like in all four channels (scales are shown in the top-right panel). The dashed vertical lines are thresholds for hit selection in the corresponding channel. Shown in the upper right corner of each panel is the Pearson correlation coefficient (in all cases, p < 0.01 after Bonferroni correction)

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