Table 1 Comparison of the four latest and free softwares for in vitro pairwise drug combination analysis developed during the period 2016−2018
Features | COMBImage | COMBIA | SynergyFinder | Combenefit | |
|---|---|---|---|---|---|
Cell viability | Synergy/antagonism models | B, RB, T, RT | B, L, T | B, L, HSA, ZIP | B, L, HSA, SANE |
|  | Non-parametric statistics | + | + | − | − |
| Â | Graphics | + | + | + | + |
| Â | Result tables | + | + | + | + |
TLVM | Morphological changes | + | − | − | − |
|  | Confluence changes | + | − | − | − |
|  | MapReduce | + | − | − | − |
|  | Parameter optimization | + | − | − | − |
|  | Non-parametric statistics | + | − | − | − |
|  | Graphics | + | − | − | − |
|  | Result tables | + | − | − | − |
Other | OS | Windows | all | all | all |
| Â | Available as | Standalone | R-package | Web application | Standalone, M-package |