Representativeness of variation benchmark datasets

BMC Bioinformatics

Table 5 Mapping of the datasets to PDB structures and CATH domains

dataset	no. of variants mapped to PDB	no. of variants mapped to CATH domain	% mapped to CATH domain (of mapped to PDB)	no. of variants with a CATH classification	% with a CATH classification (of mapped to PDB)	no. of unique CATH superfamilies
DS1	39,081	23,303	59.63	21,853	55.92	700
DS2	2358	1387	58.82	1319	55.94	319
DS3	10,242	6580	64.25	6396	62.45	239
DS4	2245	1325	59.02	1262	56.21	306
DS5	7261	4687	64.55	4556	62.75	227
DS6	1743	991	56.86	941	53.99	277
DS7	9519	6100	64.08	5920	62.19	234
DS8	1706	973	57.03	928	54.40	269
DS9	6652	4301	64.66	4170	62.69	223
DS10	1731	865	49.97	826	47.72	253
DS11	6420	4350	67.76	4212	65.61	220
DS12	150	66	44.00	62	41.33	32
DS13	481	142	29.52	135	28.07	18
DS14	953	478	50.16	454	47.64	186
DS15	3728	2557	68.59	2486	66.68	188
DS16	82	38	46.34	36	43.90	21
DS17	272	78	28.68	73	26.84	12
DS18	4494	2980	66.31	2862	63.68	274
DS19	3418	2081	60.88	2035	59.54	210
DS20	2985	2086	69.88	2031	68.04	235
DS21	10,990	7051	64.16	6786	61.75	402
DS22	2169	1301	59.98	1217	56.11	291
DS23	10,290	6566	63.81	6353	61.74	307
DS24	12,749	7828	61.40	7499	58.82	347

ISSN: 1471-2105