Table 3 Enriched GO terms in up and down-regulated genes
From: iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data
Direction | Pathways | nGenes | adj.Pval |
|---|---|---|---|
Down Regulated | Cell cycle | 259 | 4.50E-46 |
Cell cycle process | 207 | 1.70E-42 | |
Mitotic cell cycle | 169 | 5.60E-38 | |
Chromosome segregation | 92 | 2.80E-35 | |
Mitotic cell cycle process | 145 | 2.00E-33 | |
Sister chromatid segregation | 72 | 5.20E-33 | |
Cell division | 118 | 5.20E-33 | |
Nuclear chromosome segregation | 80 | 2.20E-30 | |
Nuclear division | 86 | 5.60E-26 | |
Organelle organization | 350 | 1.20E-24 | |
Mitotic nuclear division | 65 | 3.50E-24 | |
Organelle fission | 88 | 5.80E-24 | |
Cytoskeleton organization | 159 | 1.70E-23 | |
Cell cycle phase transition | 98 | 2.60E-21 | |
Mitotic sister chromatid segregation | 45 | 4.00E-21 | |
Up Regulated | Cell surface receptor signaling pathway | 258 | 3.40E-25 |
Regulation of cell proliferation | 171 | 8.20E-23 | |
Cell proliferation | 195 | 7.40E-22 | |
Regulation of signaling | 265 | 3.80E-21 | |
Response to organic substance | 259 | 1.20E-20 | |
Regulation of cell communication | 260 | 1.20E-20 | |
Locomotion | 165 | 1.20E-19 | |
Regulation of signal transduction | 239 | 1.30E-19 | |
System development | 332 | 1.00E-18 | |
Regulation of cellular component movement | 100 | 3.70E-17 | |
Regulation of response to stimulus | 291 | 8.20E-17 | |
Response to endogenous stimulus | 143 | 1.20E-16 | |
Response to chemical | 319 | 1.70E-16 | |
Cellular response to organic substance | 211 | 1.80E-16 | |
Cell migration | 131 | 2.10E-16 |