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Table 4 Enriched transcription factor (TF) binding motifs

From: iDEP: an integrated web application for differential expression and pathway analysis of RNA-Seq data

Direction Pathways nGenes adj.Pval
Down
Regulated
Tftargets:TF Target SP1 475 9.80E-23
Tftargets:TF Target E2F-4 65 9.80E-23
TFactS E2F1 43 1.10E-16
TRRUST:TF Target E2F1 37 9.70E-15
RegNetwork:TF Target E2F4 127 1.20E-14
RegNetwork:TF Target E2F1 208 1.00E-13
TFactS E2F4 20 1.30E-12
RegNetwork:TF Target NFYA 154 4.60E-09
TFactS E2F3 15 1.80E-08
Tftargets:TF Target TEAD1 33 1.90E-08
Tftargets:TF Target AP1 74 2.30E-08
TFactS E2F2 14 2.60E-08
Tftargets:TF Target TGIF1 34 3.30E-08
Tftargets:TF Target ZNF219 60 4.50E-08
Tftargets:TF Target HF1H3B 101 5.00E-08
Up
Regulated
Tftargets:TF Target NFKB 54 4.90E-09
TFactS FOXO3 21 4.90E-09
Tftargets:TF Target NFKB1 34 7.30E-09
TRRUST:TF Target NFKB1 42 7.30E-09
TFactS CTNNB1 40 4.40E-08
Tftargets:TF Target FOXJ1 22 2.00E-07
Tftargets:TF Target POU3F2 35 4.00E-07
TRRUST:TF Target RELA 38 4.20E-07
Tftargets:TF Target FOXO3 28 4.80E-07
TRRUST:TF Target SP1 50 4.80E-07
TRRUST:TF Target JUN 25 5.20E-07
TRRUST:TF Target EGR1 19 6.10E-07
Tftargets:TF Target SP1 39 1.20E-06
Tftargets:TF Target FOXJ3 25 1.20E-06
Tftargets:TF Target FOXL1 24 1.20E-06