Fig. 2
From: SMuRF: a novel tool to identify regulatory elements enriched for somatic point mutations
Significantly mutated regions identified by SMuRF. Each of the 72 genomic intervals that passed the significance (q-value ≤0.05) and mutation rate filters are represented. The negative log of the q-value calculated from the binomial test for each region is plotted against the number of unique samples with a mutation within that region. The most frequently and most significantly mutated regions include the promoters of both known and novel genes of interest in liver cancer