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Table 1 Method Performance Estimates

From: Capturing context-specific regulation in molecular interaction networks

A. Sensitivity

Genes

  

Links

  
 

LIMMA

BioNet

CoNE

LIMMA

BioNet

CoNE

Topology

-0.002

-0.303

0.302

0.011

-0.360

-0.009

Network Size

-0.129

-0.608

-0.177

-0.188

-0.386

-0.186

B. Specificity

Genes

  

Links

  
 

LIMMA

BioNet

CoNE

LIMMA

BioNet

CoNE

Topology

-0.079

-0.151

-0.659

0.217

0.687

-0.0306

Network Size

0.497

1.025

0.865

1.266

1.253

0.970

C. Precision

Genes

  

Links

  
 

LIMMA

BioNet

CoNE

LIMMA

BioNet

CoNE

Topology

-0.000

-0.041

0.015

-0.020

-0.041

-0.003

Network Size

0.005

0.016

0.058

0.057

0.038

0.028

  1. Network Topology (0 for scale-free, 1 for exponential) and network size (0 for 500 genes, 1 for 2000 genes) parameter estimates for the simulations from modeling method sensitivity and specificity by logistic regression and method precision by negative binomial regression