Table 3 TOX 21 assays
Subdataset | qHTS assay target |
|---|---|
NR-AR | Androgen receptor using the MDA cell line |
NR-AR-LBD | Androgen receptor ligand binding domain |
NR-ER | Estrogen receptor α using the BG1 cell line |
NR-ER-LBD | Estrogen receptor α ligand binding domain |
NR-AhR | Aryl hydrocarbon receptor |
NR-Aromatase | Aromatase enzyme |
NR-PPAR- γ | Peroxisome proliferator-activated receptor γ |
SR-ARE | Antioxidant response element |
SR-ATAD5 | Luciferase-tagged ATAD5 in human embryonic kidney cells |
SR-HSE | Heat shock response |
SR-MMP | Mitochondrial membrane potential |
SR-p53 | p53 response |