From: Predicting protein-protein interactions using high-quality non-interacting pairs
Method | Negative samples | ACC | PE | RE | SPE | MCC | F1 | AUC |
---|---|---|---|---|---|---|---|---|
Our method | Sub | 93.79% ± 0.43% | 95.18% ± 0.41% | 92.25% ± 0.78% | 95.33% ± 0.45% | 87.62% ± 0.83% | 93.69% ± 0.38% | 98.13% ± 0.17% |
 | NIP-SS | 94.34% ± 0.38% | 95.62% ± 0.75% | 92.96% ± 0.40% | 95.74% ± 0.75% | 88.73% ± 0.77% | 94.27% ± 0.34% | 98.24% ± 0.11% |
 | NIP-RW | 87.92% ± 0.24% | 90.04% ± 1.69% | 85.32% ± 1.90% | 90.48% ± 2.20% | 75.97% ± 0.55% | 87.59% ± 0.35% | 94.23% ± 0.12% |
Du’s work [27] | Sub | 92.58% ± 0.38% | 94.21% ± 0.45% | 90.95% ± 0.41% | 94.41% ± 0.45% | 85.41% ± 0.76% | 92.55% ± 0.39% | 97.55% ± 0.16% |
 | NIP-SS | 94.44% ± 0.35% | 95.46% ± 0.38% | 93.44% ± 0.45% | 95.45% ± 0.41% | 88.90% ± 0.68% | 94.44% ± 0.37% | 98.22% ± 0.20% |
 | NIP-RW | 88.59% ± 0.32% | 92.61% ± 0.41% | 84.14% ± 0.43% | 93.13% ± 0.35% | 77.52% ± 0.59% | 88.17% ± 0.34% | 94.73% ± 0.18% |
You’s work [25] | Sub | 89.15% ± 0.33% | 90.00% ± 0.57% | 88.10% ± 0.17% | 90.21% ± 0.61% | 78.33% ± 0.67% | 89.04% ± 0.31% | 94.78% ± 0.21% |
 | NIP-SS | 94.42% ± 0.47% | 96.71% ± 0.47% | 91.96% ± 0.64% | 96.87% ± 0.46% | 88.94% ± 0.92% | 94.28% ± 0.49% | 98.46% ± 0.12% |
 | NIP-RW | 86.03% ± 0.43% | 89.19% ± 0.60% | 82.00% ± 0.70% | 90.06% ± 0.64% | 72.30% ± 0.85% | 85.44% ± 0.46% | 93.33% ± 0.46% |
Zhou’s work [23] | Sub | 88.76% ± 0.37% | 89.44% ± 0.27% | 87.89% ± 0.45% | 89.62% ± 0.30% | 77.53% ± 0.53% | 88.66% ± 0.28% | 94.69% ± 0.31% |
 | NIP-SS | 92.10% ± 0.34% | 93.48% ± 0.45% | 90.51% ± 0.73% | 93.68% ± 0.49% | 84.24% ± 0.67% | 91.97% ± 0.37% | 97.29% ± 0.16% |
 | NIP-RW | 82.64% ± 0.33% | 83.98% ± 0.34% | 80.67% ± 0.48% | 84.61% ± 0.36% | 65.34% ± 0.65% | 82.30% ± 0.35% | 90.00% ± 0.39% |
Yang’s work [22] | Sub | 84.81% ± 0.37% | 87.53% ± 0.14% | 81.18% ± 0.84% | 88.44% ± 0.18% | 69.80% ± 0.71% | 84.23% ± 0.47% | 90.03% ± 0.31% |
 | NIP-SS | 89.18% ± 0.35% | 93.34% ± 0.33% | 84.38% ± 0.53% | 93.98% ± 0.31% | 78.73% ± 0.69% | 88.64% ± 0.38% | 95.50% ± 0.20% |
 | NIP-RW | 83.98% ± 0.48% | 86.09% ± 0.67% | 81.07% ± 0.80% | 86.89% ± 0.76% | 68.09% ± 0.97% | 83.50% ± 0.51% | 91.45% ± 0.27% |
Guo’s work [21] | Sub | 87.88% ± 0.56% | 88.16% ± 0.90% | 87.53% ± 0.59% | 88.24% ± 1.02% | 75.77% ± 1.12% | 87.84% ± 0.53% | 93.69% ± 0.33% |
 | NIP-SS | 90.00% ± 0.43% | 90.45% ± 0.68% | 89.45% ± 0.69% | 90.55% ± 0.77% | 80.01% ± 0.86% | 89.94% ± 0.43% | 95.02% ± 0.27% |
 | NIP-RW | 82.43% ± 0.27% | 83.48% ± 0.40% | 80.87% ± 0.45% | 83.99% ± 0.49% | 64.89% ± 0.54% | 82.15% ± 0.27% | 89.04% ± 0.33% |